Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Recruiting · Phase 3 · NCT06937086
Conditions: Ulcerative Colitis, Obesity or Overweight
At a glance
- Research payments reported, 2025
- $230,051
- U.S. investigators named
- 9
- Sites paid
- 9
- Planned or actual enrollment
- 350
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Mirikizumab (drug), Mirikizumab (drug), Tirzepatide (drug), Placebo (drug)
- Dates
- Started 2025-06-26; completion 2028-04
- Results posted
- Not yet
The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo, leads to decrease or disappearance of UC symptoms, and loss of at least one-tenth of the overall body weight. Participation in this study will last up to 61 weeks, including 52 weeks of treatment.
From ClinicalTrials.gov, last updated 2026-11-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $230,051 in research payments for this study in 2025 (10 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Dennis S. Riff, M.D. Specialist · Anaheim, CA
- Udayakumar Navaneethan, MD Gastroenterology · Saint Petersburg, FL
- Jeffrey Schneider, M.D. Gastroenterology · Coral Springs, FL
- Alexander Veloso, MD Gastroenterology · Miami, FL
- Son V. Nguyen, M.D. Gastroenterology · New Iberia, LA
- Paul S. Sepe, MD Gastroenterology · Dartmouth, MA
- Erica R. Cohen, M.D. Gastroenterology · Chevy Chase, MD
- Melvyn M. Acosta, M.D. Gastroenterology · Hato Rey, PR
- Jeff Bullock, M.D. Gastroenterology · San Antonio, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Research Associates of South Florida LLC $70,011
- Precision Clinical Research LLC $42,418
- Orlando Health, FL $29,495
- Southern Star Research Institute LLC $26,007
- Care Access Research LLC $22,759
- 121 Domenech Ave $21,740
- Smart Cures Clinical Research LLC $10,100
- Lucida Clinical Trials $6,357
- Childrens Center for Digestive Health Care LLC $1,015
- $150
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.