Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Recruiting · Phase 3 · NCT06937099
Conditions: Crohn's Disease, Obesity or Overweight
At a glance
- Research payments reported, 2025
- $258,435
- U.S. investigators named
- 8
- Sites paid
- 8
- Planned or actual enrollment
- 290
About the trial
- Sponsor
- Eli Lilly and Company
- Tested
- Mirikizumab (drug), Mirikizumab (drug), Tirzepatide (drug), Placebo (drug)
- Dates
- Started 2025-06-26; completion 2028-05
- Results posted
- Not yet
The main purpose of this study is to evaluate the efficacy and safety of mirikizumab and placebo compared with mirikizumab and concomitantly administered tirzepatide in adult participants with moderately to severely active CD and obesity, or overweight. The maximum duration of this study is up to 61 weeks.
From ClinicalTrials.gov, last updated 2026-11-04. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Eli Lilly and Company reported $258,435 in research payments for this study in 2025 (9 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Udayakumar Navaneethan, MD Gastroenterology · Saint Petersburg, FL
- Jeffrey Schneider, M.D. Gastroenterology · Coral Springs, FL
- Alexander Veloso, MD Gastroenterology · Miami, FL
- Son V. Nguyen, M.D. Gastroenterology · New Iberia, LA
- Erica R. Cohen, M.D. Gastroenterology · Chevy Chase, MD
- Melvyn M. Acosta, M.D. Gastroenterology · Hato Rey, PR
- Jeff Bullock, M.D. Gastroenterology · San Antonio, TX
- George A. Duvall, M.D. Gastroenterology · Tyler, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Precision Clinical Research LLC $86,369
- Southern Star Research Institute LLC $42,613
- Orlando Health, FL $29,495
- 121 Domenech Ave $28,295
- Tyler Research Institute LLC $25,390
- Care Access Research LLC $23,849
- Research Associates of South Florida LLC $21,651
- $500
- Childrens Center for Digestive Health Care LLC $274
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.