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A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

Recruiting · Phase 2 · NCT06972446

Conditions: Rheumatoid Arthritis

At a glance

Research payments reported, 2025
$668,972
U.S. investigators named
28
Sites paid
26
Planned or actual enrollment
180

About the trial

Sponsor
AbbVie
Tested
Lutikizumab (drug), Placebo (drug), Ravagalimab (drug)
Dates
Started 2025-06-20; completion 2027-11
Results posted
Not yet

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. This study will evaluate the efficacy and safety of targeted therapies through a series of substudies for the treatment of moderately to severely active Rheumatoid Arthritis (RA). This study currently includes 3 substudies evaluating different treatments in participants with RA. Substudy 1 will evaluate lutikizumab monotherapy (treatment given alone) compared to placebo (looks like the study treatment but contains no medicine). Substudy 2 will evaluate ravagalimab monotherapy compared to placebo and Substudy 3 will evaluate lutikizumab and ravagalimab combination thera…

From ClinicalTrials.gov, last updated 2026-10-08. Full record, eligibility and contacts (opens in a new tab)

Industry funding

AbbVie Inc. reported $668,972 in research payments for this study in 2025 (75 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Clinical Research of West Florida $116,512
  • Dynamed Clinical Research LP $107,189
  • Sweet Hope Research Specialty Inc $53,449
  • Tekton Research LLC $50,579
  • Accurate Clinical Research Inc $32,338
  • Research Physicians Network LLC $25,681
  • Paramount Medical Research $21,842
  • Aa Mrc LLC $21,690
  • Djl Clinical Research PLLC $20,024
  • Epic Medical Research $18,300
  • Corazon USA LLC $17,075
  • Reuviva Research Center LLC $16,024
  • Albuquerque Center for Rheumatology $15,629
  • Hmd Research LLC $15,400
  • Advanced Clinical Research Center $14,024
  • Willow Rheumatology and Wellness $14,000
  • West Tennessee Research Institute $13,024
  • Arthritis and Rheumatology $12,985
  • Joint and Muscle Research Institute $12,674
  • Clinical Research Investigator $12,500
  • Altoona Center for Clinical Researc $12,500
  • Newport Huntington Medical Group $12,024
  • Deerbrook Medical Associates $10,903
  • Inland Rheumatology Clinical Trials $10,903
  • David S Hallegua MD A Prof Corp $10,903
  • Scla Management LLC $800

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.