A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Recruiting · Phase 3 · NCT06976216
Conditions: Alzheimer's Disease
At a glance
- Research payments reported, 2025
- $50,457
- U.S. investigators named
- 17
- Sites paid
- 17
- Planned or actual enrollment
- 586
About the trial
- Sponsor
- Bristol-Myers Squibb
- Tested
- KarXT (drug), KarX-EC (drug), Placebo (other)
- Dates
- Started 2025-07-14; completion 2029-02-23
- Results posted
- Not yet
The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease
From ClinicalTrials.gov, last updated 2026-10-27. Full record, eligibility and contacts (opens in a new tab)
Industry funding
E.r. Squibb & Sons, L.l.c. reported $50,457 in research payments for this study in 2025 (18 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Donald L. Anderson, M.D. Psychiatry · Banning, CA
- Dung Trinh, MD Internal Medicine · Mission Viejo, CA
- Alison B. Allen, MD Neurology · Basalt, CO
- Adam D. Falchook, MD Neurology · Stuart, FL
- Muhammed W. Niazi, MD Neurology · Rockledge, FL
- Linda Pao, MD Neurology · Jupiter, FL
- Julie B. Schwartzbard, MD Neurology · Aventura, FL
- Christopher P. Recknor, M.D. Internal Medicine · Gainesville, GA
- Antonio H. Iglesias, M.D. Neurology · Maywood, IL
- Jeffrey A. Norton, M.D. Pain Medicine · Lawrence, MA
- Patricia M. Walsh, M.D. Psychiatry · Lynn, MA
- Mohammad R. Bolouri, MD Neurology · Matthews, NC
- Arun Singh, M.D. Emergency Medicine · Toms River, NJ
- Sharon A. Brangman, MD Geriatric Medicine · Syracuse, NY
- Douglas W. Scharre, MD Neurology · Columbus, OH
- John A. Stoukides, MD Geriatric Medicine · East Providence, RI
- Joseph A. Oommen, MD Neurology · Beaumont, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Center for Advanced Research & Education $6,796
- Gadolin Research, Llc $6,792
- Charter Research, Llc $4,772
- Healthy Brain Clinic $4,373
- $3,100
- Adams Clinical Harlem $3,037
- Alzheimers Memory Center Flourish Research $2,786
- Jem Research Institute $2,705
- Alzheimers Research and Treatment Center $2,503
- Visionary Investigators Network $2,491
- Mountain Neurological Research Center $1,540
- Ohio State University $1,444
- Anderson Clinical Research $1,437
- Rhode Island Mood & Memory Research Institute $1,424
- Merritt Island Medical Research $1,393
- Re:cognition Health - Chicago $1,374
- Suny Upstate Medical University $1,367
- Advanced Memory Research Institute of New Jersey $1,122
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.