A Phase 1 Study of BMS-986500 as Monotherapy or Combination Therapy in Advanced Solid Tumors
Recruiting · Phase 1 · NCT06997029
Conditions: Advanced Solid Tumor, Advanced Breast Cancer, Advanced Ovarian Cancer
At a glance
- Research payments reported, 2025
- $29,063
- U.S. investigators named
- 7
- Sites paid
- 7
- Planned or actual enrollment
- 234
About the trial
- Sponsor
- Bristol-Myers Squibb
- Tested
- BMS-986500 (drug), Palbociclib (drug), Fulvestrant (drug)
- Dates
- Started 2025-08-01; completion 2028-12-14
- Results posted
- Not yet
The purpose of this study is to assess BMS-986500 as monotherapy in advanced solid tumors and as combination therapy in CDK4/6 inhibitor pre-treated advanced breast cancer.
From ClinicalTrials.gov, last updated 2026-10-06. Full record, eligibility and contacts (opens in a new tab)
Industry funding
E.r. Squibb & Sons, L.l.c. reported $29,063 in research payments for this study in 2025 (7 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Mehmet Akce, M.D Hematology & Oncology · Birmingham, AL
- Yung Lyou, M.D., PH.D. Hematology & Oncology · Fullerton, CA
- Cyrus Mazidi, M.D. Hematology & Oncology · Greenbrae, CA
- Faisal Fa'ak, MD Medical Oncology · Saint Louis, MO
- Lionel D. Lewis, M.D. Internal Medicine · Lebanon, NH
- Ezra Rosen Medical Oncology · New York, NY
- David Sommerhalder Hematology & Oncology · San Antonio, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Memorial Sloan-Kettering Cancer Center - Cancer $7,732
- Next Oncology $5,308
- Marin Cancer Care, Incorporated $4,859
- University of Alabama Hospital, AL $4,357
- St. Jude Medical Center Lab $2,358
- Washington University School of Medicine Cardiovascular Division $2,320
- Mary Hitchcock Memorial Hospital, NH $2,130
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.