Phase 3 Randomized, Modified Double-blind, Active-controlled Safety Study on vYF in Adults
Completed · Phase 3 · NCT07002060
Conditions: Yellow Fever Immunization
At a glance
- Research payments reported, 2025
- $415,611
- U.S. investigators named
- 8
- Sites paid
- 7
- Planned or actual enrollment
- 640
About the trial
- Sponsor
- Sanofi
- Tested
- Yellow fever vaccine (live) (biological), YF vaccine (live) (biological)
- Dates
- Started 2025-05-22; completion 2026-01-20
- Results posted
- Not yet
The purpose of this study is to assess the safety of vYF (investigational vaccine) compared to the safety of YF-VAX (YF licensed vaccine) in adults aged 18 years up to 60 years. Study details include: * The study duration will be up to approximately 6 months. * One single dose of the study intervention (vYF or YF-VAX) will be administered subcutaneously at the 1st visit. * The visit(V) frequency will be Day(D) 01 (V01) and D29 (V02). Two telephone calls will be planned at D15 and Month(M)6. Number of Participants: A total of 640 participants are expected to be included in the study in a 3:1 ratio (vYF: YF-VAX): Group 1: vYF; N=480 Group 2: YF-VAX; N=160 Study Arms and Duration: Randomized…
From ClinicalTrials.gov, last updated 2026-02-02. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Sanofi Pasteur Inc. reported $415,611 in research payments for this study in 2025 (34 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Srilatha Edupuganti, MD Infectious Disease · Atlanta, GA
- Scott P. Striplin, M.D. OB-GYN (Obstetrics & Gynecology) · Covington, LA
- Kawsar R. Talaat, M.D. Infectious Disease · Baltimore, MD
- Sarah George, M.D. Infectious Disease · Saint Louis, MO
- Brandon J. Essink, M.D. Family Medicine · Creighton, NE
- Matthew G. Davis, MD Family Medicine · Rochester, NY
- David Fried, MD Internal Medicine · East Greenwich, RI
- James T. Peterson, MD OB-GYN (Obstetrics & Gynecology) · Salt Lake City, UT
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Atlas Clinical Research Llc $187,235
- Velocity Clinical Research $107,460
- Velocity Clinical Research,inc $43,002
- J Lewis Research,incorporation $36,645
- Saint Louis University Neurosurge $29,644
- Emory University Hospital, GA $6,820
- Johns Hopkins University $4,806
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.