An Open-label, Multicenter Study to Assess the Pharmacokinetics (PK), Safety, and Tolerability of Subcutaneous IgPro20 in Immunoglobulin (IG) Treatment-naïve Participants With Primary Immunodeficiency (PID)
Completed · Phase 4 · NCT07076446
Conditions: Primary Immunodeficiency
At a glance
- Research payments reported, 2025
- $561,075
- U.S. investigators named
- 7
- Sites paid
- 9
- Planned or actual enrollment
- 8
About the trial
- Sponsor
- CSL Behring
- Tested
- IgPro (biological)
- Dates
- Started 2025-07-15; completion 2026-06-30
- Results posted
- Not yet
This is an open-label, multicenter, phase 4 study in IG treatment-naïve participants with PID, conducted in the United States (US), to assess the PK, safety, and tolerability of IgPro20. The primary objective of this study is to characterize the PK of IgPro20 and to assess the safety and tolerability of IgPro20 in IG treatment-naïve participants with PID who are aged greater than or equal to (\>=) 18 years.
From ClinicalTrials.gov, last updated 2026-07-16. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Csl Behring reported $561,075 in research payments for this study in 2025 (162 payments).
Products named: Hizentra
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Connie Hsu, MD Allergy & Immunology · Litchfield Park, AZ
- Michael E. Manning, MD Allergy & Immunology · Scottsdale, AZ
- Isaac Melamed, M.D. Specialist · Centennial, CO
- Antoine Azar, M.D. Allergy & Immunology · Baltimore, MD
- Jason P. Raasch, MD Allergy & Immunology · Plymouth, MN
- Jennifer M. Monroy, MD Allergy & Immunology · Saint Louis, MO
- Michael J. Palumbo, M.D. Allergy & Immunology · Pittsburgh, PA
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- $180,061
- Research Solutions of Arizona (dcrpi) $137,569
- Washington University $121,788
- Immunoe Health Centers $37,143
- Allergy & Clinical Immunology Associates $23,812
- Elligo Health Research, Inc $20,173
- Mngi Digestive Health - Plymouth Endoscopy Center & Clinic $17,629
- Johns Hopkins Institute for Assured Autonomy (iaa) Clinical Research $13,130
- Allergy Asthma and Immunology Associates South Scottsdale Office $8,808
- VA Minneapolis Health Care $962
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.