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A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia

Recruiting · Phase 2 · NCT07145918

Conditions: Schizophrenia

At a glance

Research payments reported, 2025
$210,155
U.S. investigators named
5
Sites paid
6
Planned or actual enrollment
268

About the trial

Sponsor
AbbVie
Tested
Emraclidine (drug), Placebo (drug)
Dates
Started 2025-08-04; completion 2028-02
Results posted
Not yet

Schizophrenia is a common and severe psychiatric illness characterized by extreme disturbances of cognition and thought, affecting language, perception and sense of self. This study will assess adverse events, change in disease activity, and how oral emraclidine moves through the body in adult participants with schizophrenia Emraclidine is an investigational drug being developed for the treatment of schizophrenia. Participants are placed in one of two parts, Part A or Part B, where each group will receive a different treatment. Participants will receive either oral emraclidine or placebo. Approximately 268 participants will be enrolled across roughly 32 sites in the United States. Partici…

From ClinicalTrials.gov, last updated 2026-09-15. Full record, eligibility and contacts (opens in a new tab)

Industry funding

AbbVie Inc. reported $210,155 in research payments for this study in 2025 (9 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Pillar Clinical Research LLC $181,496
  • Community Clinical Research Inc $23,118
  • St Louis Clinical Trials $1,440
  • Community Clinical Research $1,440
  • Cbh Health LLC $1,385
  • Parexel International LLC $1,275

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.