Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration
Recruiting · Phase 1, Phase 2 · NCT07160179
Conditions: Geographic Atrophy, Age-Related Macular Degeneration
At a glance
- Research payments reported, 2025
- $113,826
- U.S. investigators named
- 4
- Sites paid
- 5
- Planned or actual enrollment
- 66
About the trial
- Sponsor
- AbbVie
- Tested
- ABBV-6628 (drug), SYFOVRE (drug)
- Dates
- Started 2025-08-13; completion 2029-10
- Results posted
- Not yet
Age-related macular degeneration (AMD) is the abnormal growth of new blood vessels in the light-sensitive tissue at the back of the eye called the retina. Geographic Atrophy (GA) is an advanced form of dry AMD. The purpose of this study is to assess the adverse events and how intravitreal ABBV-6628 moves through the body of adult participants with secondary to age-related macular degeneration ABBV-6628 is an investigational monoclonal antibody fragment being developed for the treatment of geographic atrophy (GA) secondary to (AMD) age-related macular degeneration. Participants in the Stage 1 part will be placed in 1 of 4 groups, called treatment arms. Participants in Stage 2 will be place…
From ClinicalTrials.gov, last updated 2026-07-13. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $113,826 in research payments for this study in 2025 (12 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Raj K. Maturi, MD Retina Specialist · Carmel, IN
- Kameran Lashkari, M.D. Ophthalmology · North Dartmouth, MA
- Karl G. Csaky, MD Ophthalmology · Dallas, TX
- Sunil S. Patel, MD, PHD Ophthalmology · Abilene, TX
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- Retina Foundation of the Southwest $47,372
- Raj K Maturi MD PC $35,212
- Retina Research Institute of Texas $17,575
- Integrated Clinical Research LLC $7,000
- Advanced Eye Research Associates $6,667
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.