Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Recruiting · Phase 2 · NCT07175428
Conditions: Atrial Fibrillation (AF)
At a glance
- Research payments reported, 2025
- $88,889
- U.S. investigators named
- 4
- Sites paid
- 4
- Planned or actual enrollment
- 1,200
About the trial
- Sponsor
- Regeneron Pharmaceuticals
- Tested
- REGN7508 (drug), REGN9933 (drug), Apixaban (drug)
- Dates
- Started 2025-10-20; completion 2027-04-21
- Results posted
- Not yet
This study is researching experimental drugs called REGN7508 and REGN9933. The study is focused on participants who have atrial fibrillation, which means that the heart beats too fast and unevenly. REGN7508 and REGN9933 are designed to help stop blood clots forming in patients with atrial fibrillation. The aim of the study is to see how well REGN7508 and REGN9933 work in patients that get medicine for their atrial fibrillation. The bleeding effects of REGN7508 and REGN9933 will be compared to another medicine (apixaban), which is available on the market to treat and prevent formation of blood clots. The study is looking at several other research questions, including: * What side effects m…
From ClinicalTrials.gov, last updated 2026-11-05. Full record, eligibility and contacts (opens in a new tab)
Industry funding
Regeneron Pharmaceuticals, Inc. reported $88,889 in research payments for this study in 2025 (159 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Ashit Jain, M.D. Cardiology · Fremont, CA
- Farhad Rafii, M.D. Cardiology · West Hills, CA
- Mahfouz El Shahawy, MD Cardiology · Sarasota, FL
- Alexis Gutierrez, M.D. Cardiology · Hialeah, FL
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- $28,550
- Mission Cardiovascular Research Institute $27,192
- Inpatient Research Clinic LLC $25,544
- Elegant Research and Development LLC $3,900
- Cardiovascular Center of Sarasota Foundation for Research and Education $3,703
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.