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Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

Recruiting · Phase 3 · NCT07190209

Conditions: Chronic Obstructive Pulmonary Disease

At a glance

Research payments reported, 2025
$2.0M
U.S. investigators named
86
Sites paid
78
Planned or actual enrollment
942

About the trial

Sponsor
Sanofi
Tested
Lunsekimig (drug), Placebo (drug)
Dates
Started 2025-09-16; completion 2030-01-22
Results posted
Not yet

This is a parallel, Phase 2b/Phase 3, 3-arm study to investigate the efficacy, safety, and tolerability of subcutaneous (SC) treatment with lunsekimig compared with placebo in adult participants (aged 40 to 80 years, inclusive) with inadequately controlled Chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype. Participation to the study consists of 3 periods: * Screening period of up to 4 weeks * Randomized intervention period of approximately 48 weeks * Follow-up period: Approximately 8 weeks The study duration will be up to 60 weeks.

From ClinicalTrials.gov, last updated 2026-10-19. Full record, eligibility and contacts (opens in a new tab)

Industry funding

Sanofi US Services Inc. reported $2.0M in research payments for this study in 2025 (117 payments).

Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.

U.S. investigators named on this study

Clinicians the company named as principal investigators in its Open Payments reports.

Sites paid to run it

  • Helix Biomedics Llc $120,596
  • Interspond LLC $98,600
  • Deluxe Health Center $95,663
  • Epic Medical Research Llc $82,176
  • Elligo Health Research Inc $70,151
  • Synergry Groups Medical Llc $58,650
  • National Clinical Trials Inc $48,904
  • Newportnativemd Inc $46,358
  • Preferred Primary Care Physicians,inc $38,178
  • Finlay Medical Research Corp $37,420
  • Clinical Research Trials of Florida $36,729
  • Bioluminux Clinical Research New Jersey $33,352
  • Imax Clinical Trials Llc 1 $29,834
  • Trio Clinical Trials Llc $29,834
  • Omega Research Debary Llc $29,550
  • Hmd Research Llc $29,460
  • Paradigm Clinical Research Centers, Inc $29,440
  • Rex Clinical Trials Llc $29,000
  • Lucida Clinical Trails Llc $29,000
  • Novel Research Llc $27,528
  • Medrasa Clinical Research Llc $27,486
  • Alliance Clinical Holdings Llc $27,058
  • Qcare Site Services Inc $26,750
  • Advanced Pulmonary Research Institute of Michigan PLLC $26,322
  • Dct Health Central Womens Care Llc Dba Discovery Clinical Trails $26,229
  • Innovo Research Inc $25,854
  • Vitalis Clinical Research Center Ll $25,533
  • Southeastern Research Center LLC $24,510
  • Clincare Llc Intracare Clinical $23,260
  • Avicenna Clinical Research Dm Clinical Research $22,508
  • Care Access Research Llc $22,500
  • Bfhc Research Llc $22,070
  • Pensacola Research Consultants Inc Avanza Medical Research Center $21,000
  • Hillcrest Medical Research $20,760
  • Oregon Clinic PC $20,200
  • Stern Research PArtners Llc $20,000
  • Ib Miami LLC $19,760
  • Axsendo Clinical Research Llc $19,481
  • Kaushlendra Tripathi Medtrial Llc $19,421
  • Toledo Institute of Clinical Resear Inc $19,200
  • Ab Adams PC $18,756
  • Hannibal Regional Healthcare System Inc $18,608
  • Beautiful Minds Clinical Research Center $18,558
  • Downtown L A Research Center Inc $18,400
  • Solution Clinical Research $18,160
  • Newyorkpresbyterian Queens $17,750
  • Florida Institute for Clinical Research LLC $17,479
  • Professional Research Center $17,356
  • Nuren Medical Research Center $16,856
  • Salud Clinical Services Llc $16,356
  • Tucson Clinical Research Institute Llc $16,346
  • Premier Pulmonary Critical Care and Sleep Medicine PA $16,000
  • Mid Hudson Medical Research $15,967
  • Dct Mhr LLC Discovery Clinical Trials $15,905
  • Wake Forest University Health Science $15,585
  • Gulf Coast Clinical Trials $15,408
  • Long Beach Research Institute $15,408
  • Henderson Clinical Trials Llc $15,408
  • Hull Hull Medical Specialists LLP Broward Pulmonary and Sleep Specialists $15,229
  • Dl Research Solutions $14,900
  • Element Research Group Llc $14,825
  • Ethos Indy Research Llc $14,327
  • Sierra Clinical Research $14,000
  • Broward Research Center $13,856
  • Gmg Clinical Research Llc Radiance Clinical Research $13,835
  • Bolt Clinical Research $13,760
  • Vantage Clinical Trials Llc $13,508
  • Advanced Pulmonary Research Institute $13,508
  • Corsicana Medical Research PLLC $13,450
  • Anmed Health, SC $13,229
  • Appalachian Clinical Research $13,160
  • Rheumatology and Pulmonary Clinic $13,085
  • Sarasota Fl Clinical Research Llc Sarasota Clinical Research $13,085
  • Pact Center for Research PLLC $13,085
  • Alpine Clinical Research Center Inc $13,085
  • California Medical Research Inc $13,085
  • Eastern Medical Group Corporation $13,085
  • Burt Schear MD and Associates $13,085

Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.