Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
Recruiting · Phase 2 · NCT07226791
Conditions: Ventral Hernia
At a glance
- Research payments reported, 2025
- $32,500
- U.S. investigators named
- 3
- Sites paid
- 3
- Planned or actual enrollment
- 200
About the trial
- Sponsor
- AbbVie
- Tested
- AGN-151607-DP (drug), Placebo for AGN-151607-DP (drug)
- Dates
- Started 2026-02-04; completion 2030-05
- Results posted
- Not yet
A ventral hernia happens when the muscles in the front of your belly become weak and let organs push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems. This study aims to asses if AGN-151607-DP is safe and effective for closing the belly wall after open ventral hernia surgery, without needing a complex procedure. Adverse Events and change in disease activity will be assessed. AGN-151607-DP is an investigational drug being developed to treat ventral hernia. Participants will be randomly placed in treatment groups to receive either AGN151607-DP or matching placebo. Approximately 200 adult participants with midline ven…
From ClinicalTrials.gov, last updated 2026-08-25. Full record, eligibility and contacts (opens in a new tab)
Industry funding
AbbVie Inc. reported $32,500 in research payments for this study in 2025 (11 payments).
Research payments usually go to hospitals, universities and research sites to run a study, not to the investigators personally. A payment is not evidence of wrongdoing.
U.S. investigators named on this study
- Hobart W. Harris, MD General Surgery · San Francisco, CA
- Jana Sacco, MD General Surgery · Jacksonville, FL
- Michael J. Rosen, MD General Surgery · Cleveland, OH
Clinicians the company named as principal investigators in its Open Payments reports.
Sites paid to run it
- UCSF Langley Porter Psychiatric Hospital and Clinics, CA $27,615
- Cleveland Clinic, OH $2,380
- University of Florida $2,025
- $480
Sources: CMS Open Payments research payments (program year 2025) and ClinicalTrials.gov, U.S. National Library of Medicine.