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Warfarin Sodium

Brand names: Warfarin Sodium, Jantoven

Vitamin K Antagonist Oral

Part of: Blood thinners

At a glance

Medicare prescriptions, 2024
4,233,205
Medicare drug cost
$39.3M
Average cost per prescription
$9.28
Clinicians who prescribed it
97,286

Where it is prescribed

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List the prescribers in any state, county, city or ZIP code →

What it is used for

Warfarin sodium tablets are indicated for: Prophylaxis and treatment of venous thrombosis and its extension, pulmonary embolism (PE). Prophylaxis and treatment of thromboembolic complications associated with atrial fibrillation (AF) and/or cardiac valve replacement. Reduction in the risk of death, recurrent myocardial infarction (MI), and thromboembolic events such as stroke or systemic embolization after myocardial infarction. Limitations of Use Warfarin sodium tablets have no direct effect on an established thrombus, nor does it reverse ischemic tissue damage. Once a thrombus has occurred, however, the goals of anticoagulant treatment are to prevent further extension of the formed clot and to prevent secondary thromboembolic complications that may result in serious and possibly fatal sequelae.

From the FDA-approved prescribing information (label dated June 2025). Full labels on DailyMed (opens in a new tab)

Boxed warning

WARNING: BLEEDING RISK Warfarin sodium can cause major or fatal bleeding. Perform regular monitoring of INR in all treated patients. Drugs, dietary changes, and other factors affect INR levels achieved with warfarin sodium therapy. Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleeding. WARNING: BLEEDING RISK See full prescribing information for complete boxed warning. Warfarin sodium can cause major or fatal bleeding. Perform regular monitoring of INR in all treated patients. Drugs, dietary changes, and other factors affect INR levels achieved with warfarin sodium therapy. Instruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleeding.

The FDA’s strongest warning on a label. It doesn’t mean the drug is unsafe for most people; talk to your doctor or pharmacist before stopping or changing any medicine.

Who prescribes it

All prescribers, by place, name or specialty →

Share of Medicare prescriptions written by each specialty. Select one to list its prescribers.

Trend, 2019–2024

Medicare prescriptions fell 52% from 2019 to 2024.

Medicare Part D prescriptions per year, all prescribers
  • 201910,447,648
  • 20208,731,413
  • 20217,306,595
  • 20226,321,893
  • 20235,541,041
  • 20245,033,343

Biggest change by state since 2019

  • South Dakota −37%
  • Wyoming −38%
  • North Dakota −39%
  • Minnesota −39%
  • Utah −40%
  • Rhode Island (smallest change) −63%
  • Connecticut (smallest change) −62%

From CMS’s yearly state and national Part D summaries, which count every prescriber, including those CMS leaves out of its per-clinician data (fewer than 11 prescriptions). That is why these totals are higher than the count at the top of this page. Prescriptions include refills.

What it looks like

Pills from 5 makers on file. The same medicine can look different depending on who made it, so check the imprint (the letters and numbers on the pill) with your pharmacist if a refill looks different.

Aphena Pharma Solutions - Tennessee, LLC

StrengthLooks likeImprint
1 mgpink round tablet, 8 mm, scored to split in 2IG W 1
2 mgpurple round tablet, 8 mm, scored to split in 2IG W 2
2.5 mggreen round tablet, 8 mm, scored to split in 2IG W 2 1 2
3 mgbrown round tablet, 8 mm, scored to split in 2IG W 3
4 mgblue round tablet, 8 mm, scored to split in 2IG W 4
5 mgorange round tablet, 8 mm, scored to split in 2IG W 5
7.5 mgyellow round tablet, 8 mm, scored to split in 2IG W 7 1 2
10 mgwhite round tablet, 8 mm, scored to split in 2IG W 10

Pd-Rx Pharmaceuticals, Inc.

StrengthLooks likeImprint
5 mgorange oval tablet, 11 mm, scored to split in 2TV 5 1721

Preferred Pharmaceuticals Inc.

StrengthLooks likeImprint
2.5 mggreen oval tablet, 11 mm, scored to split in 2763 2 1 2 AN

Teva Pharmaceuticals USA, Inc.

StrengthLooks likeImprint
1 mgpink oval tablet, 11 mm, scored to split in 2TV 1 1712
2 mgpurple oval tablet, 11 mm, scored to split in 2TV 2 1713
2.5 mggreen oval tablet, 11 mm, scored to split in 2TV 2 1 2 1714
3 mgbrown oval tablet, 11 mm, scored to split in 2TV 3 1715
4 mgblue oval tablet, 11 mm, scored to split in 2TV 4 1716
5 mgorange oval tablet, 11 mm, scored to split in 2TV 5 1721
6 mgturquoise oval tablet, 11 mm, scored to split in 2TV 6 1718
7.5 mgyellow oval tablet, 11 mm, scored to split in 2TV 7 1 2 1719
10 mgwhite oval tablet, 11 mm, scored to split in 2TV 10 1720

Upsher-Smith Laboratories, LLC

StrengthLooks likeImprint
1 mgpink round tablet, 9 mm, scored to split in 2WRF 1 832
2 mgpurple round tablet, 9 mm, scored to split in 2WRF 2 832
2.5 mggreen round tablet, 9 mm, scored to split in 2WRF 2 1 2 832
3 mgbrown round tablet, 9 mm, scored to split in 2WRF 3 832
4 mgblue round tablet, 9 mm, scored to split in 2WRF 4 832
5 mgorange round tablet, 9 mm, scored to split in 2WRF 5 832
6 mgturquoise round tablet, 9 mm, scored to split in 2WRF 6 832
7.5 mgyellow round tablet, 9 mm, scored to split in 2WRF 7 1 2 832
10 mgwhite round tablet, 9 mm, scored to split in 2WRF 10 832

Source: DailyMed (U.S. National Library of Medicine), from each maker’s FDA drug listing. A few makers are shown, not every one. Never take a pill you can’t identify; ask a pharmacist.

Industry payments about this drug

No industry payments to clinicians named this drug in 2025.

Recalls and shortages

Not on the FDA drug shortage list.

1 recall since 2020

  • Jan 2022 · Cardinal Healthcare · Class II
    CGMP Deviations: Products were exposed to temperatures outside of the products labeled storage conditions.

See all recalls →

Recalls usually affect specific lots from one maker, not every version of a drug. Class I is the most serious; most drug recalls are Class II. FDA recalls (opens in a new tab)

Sources: CMS Medicare Part D Prescribers by Provider and Drug (2024; prescriptions include refills, and CMS hides counts under 11 per prescriber); U.S. Food and Drug Administration, openFDA (drug labels, NDC directory, enforcement reports, drug shortages); CMS Open Payments 2025; ClinicalTrials.gov. General information only, not medical advice; not yet reviewed by our medical reviewer.